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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 23.33
Human Site: S1071 Identified Species: 36.67
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S1071 H F L V E D K S L S G G A S Y
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S1071 H F L V E D K S L S G G A S Y
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 S977 L V E D K S L S G G A S Y V D
Dog Lupus familis XP_850963 1096 118584 S1073 H F L V E D K S L S G G A S Y
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 V1067 A A F L Q S L V E D R T E S A
Rat Rattus norvegicus NP_001102926 1095 118506 S1072 H F L V E D K S L S G G A S Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 Y1009 L V E D K G L Y G G A S Y V D
Chicken Gallus gallus XP_421617 1147 124543 S1124 H F L V E D K S L T G G A S Y
Frog Xenopus laevis NP_001087832 1126 123503 N1103 N L L V E D K N L N G G A S Y
Zebra Danio Brachydanio rerio XP_700597 1315 142554 S1292 H F L V E D K S N N G G A S Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 E1252 H F L I E D R E N D G S P S Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 G1127 H F L M E D K G S N A S A S Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 R1057 L S Y M V E D R T A S G P S Y
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 D855 V L S T L V E D K V L N C A S
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 D929 A Q T L L V E D R A D Q G M S
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 6.6 100 N.A. 6.6 100 N.A. 0 93.3 73.3 86.6 N.A. N.A. 53.3 N.A. 60
P-Site Similarity: 100 100 13.3 100 N.A. 20 100 N.A. 6.6 100 93.3 93.3 N.A. N.A. 66.6 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 20 0 0
P-Site Similarity: N.A. N.A. N.A. 40 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 7 0 0 0 0 0 0 0 14 20 0 54 7 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 0 14 0 60 7 14 0 14 7 0 0 0 14 % D
% Glu: 0 0 14 0 60 7 14 7 7 0 0 0 7 0 0 % E
% Phe: 0 54 7 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 7 0 7 14 14 54 54 7 0 0 % G
% His: 54 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 14 0 54 0 7 0 0 0 0 0 0 % K
% Leu: 20 14 60 14 14 0 20 0 40 0 7 0 0 0 0 % L
% Met: 0 0 0 14 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 7 0 0 0 0 0 0 7 14 20 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % P
% Gln: 0 7 0 0 7 0 0 0 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 7 7 0 7 0 0 0 0 % R
% Ser: 0 7 7 0 0 14 0 47 7 27 7 27 0 74 14 % S
% Thr: 0 0 7 7 0 0 0 0 7 7 0 7 0 0 0 % T
% Val: 7 14 0 47 7 14 0 7 0 7 0 0 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 7 0 0 0 0 14 0 67 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _